Table 3.

Measures and time points of administration to participants.

Domain	Measure	Time point
		Baseline	9-week follow-up	21-week follow-up
Emotion dysregulationa	Difficulties in Emotion Regulation Scale–18	✓	✓	✓
Pain intensityb	Numeric Rating Scale	✓	✓	✓
Pain interferenceb	PROMISc Pain Interference instrument	✓	✓	✓
Anxietyb	State-Trait Anxiety Inventory	✓	✓	✓
Depressionb	Beck Depression Inventory	✓	✓	✓
Perceived stressb	NIHd Toolbox Perceived Stress Scale	✓	✓	✓
Posttraumatic stressb	PTSDe Checklist–Civilian Version	✓	✓	✓
Social cognitionb	The Awareness of Social Inference Test	✓	✓	✓
Sleep qualityb	Medical Outcomes Study Sleep Scale	✓	✓	✓
Harm avoidanceb	Temperament and Character Inventory	✓	✓	✓
Quality of lifeb	Satisfaction with Life Scale	✓	✓	✓
Well-beingb	COMPAS-Wf scale	✓	✓	✓
Medication and health interventions	Health Utilization Questionnaire	✓	✓	✓
Medication and health interventions	Medication and health interventions	✓	✓	✓
Acceptabilityb,g	DBTh Ways of Coping Checklist (DBT skills)	✓	✓	✓
Acceptability	Usefulness, Satisfaction, and Ease of Use Questionnaire		✓	✓
Acceptability	Patient Global Impression of Change		✓	✓
Acceptability	Semistructured interviews		✓
Acceptability	Treatment adherence		✓	✓

^aPrimary outcome.

^bSecondary outcome.

^cPROMIS: Patient-Reported Outcomes Measurement Information System.

^dNIH: National Institutes of Health.

^ePTSD: posttraumatic stress disorder.

^fCOMPAS-W: Composure, Own-worth, Mastery, Positivity, Achievement, Satisfaction with Life–Well-being.

^gUsing the listed quantitative and qualitative measures, seven domains of acceptability will be assessed according to the theoretical framework of acceptability [48]: (1) affective attitude, (2) burden, (3) ethicality, (4) intervention coherence, (5) opportunity costs, (6) perceived effectiveness, and (7) self-efficacy.

^hDBT: dialectical behavioral therapy.