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. 2023 Jun 8;14:1181973. doi: 10.3389/fimmu.2023.1181973

Table 5.

Single dose of multiple intraperitoneal injections of lipopolysaccharide.

LPS Dose (mg/kg) NO. of studies using dose Use this dose p-value Study Design
YES NO Percentage (%)
0.5 27 8 19 29.63 0.535 Once a day for 10 days
Once a day for 6 days
Once a day for 7 days
Once a day for 4 days
0.83 27 6 21 22.22 1.000 Once a day for 5 days
Once a day for 3 days
Once a day for 2 days
The interval between injections was 16 h
1 27 6 21 22.22 0.250 Once a day for 5 days
Once a day for 2 days
0.1 27 2 25 7.41 1.000 Once a day for 4 days
Twice a week for 21 days
2 27 2 25 7.41 1.000 Once a day for 3 days
1.2 27 1 26 3.70 1.000 Once a day for 7 days
0.083 27 1 26 3.70 1.000 Once a day for 4 days
0.25 27 1 26 3.70 Once a day for 7 days