TABLE 2.
Baseline demographics and hippocampal and entorhinal cortex volume.
| Variables at baseline | NC (n = 194) | MCI (n = 284) | AD (n = 130) | p-value |
| Sex (M/F) | 96/98 | 181/103 | 60/70 | 0.003 |
| Age (mean ± SD) | 74.9 (5.2) | 71.8 (8.1) | 75.0 (7.5) | 0.588 |
| MMSE score (mean ± SD) | 29 (1.1) | 27 (1.4) | 23 (2.2) | 0.000 |
| Entorhinal cortex volume (mm3) | 1930 (284) | 1719 (384) | 1417 (348) | <0.001 |
| Hippocampal volume (mm3) | 3539 (413) | 3243 (461) | 2892 (474) | <0.001 |
NC, normal controls; MCI, mild cognitive impairment; AD, Alzheimer’s disease; MMSE, mini mental state examination; SD, standard deviation.