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. 2023 Jun 7;15:1149871. doi: 10.3389/fnagi.2023.1149871

TABLE 2.

Baseline demographics and hippocampal and entorhinal cortex volume.

Variables at baseline NC (n = 194) MCI (n = 284) AD (n = 130) p-value
Sex (M/F) 96/98 181/103 60/70 0.003
Age (mean ± SD) 74.9 (5.2) 71.8 (8.1) 75.0 (7.5) 0.588
MMSE score (mean ± SD) 29 (1.1) 27 (1.4) 23 (2.2) 0.000
Entorhinal cortex volume (mm3) 1930 (284) 1719 (384) 1417 (348) <0.001
Hippocampal volume (mm3) 3539 (413) 3243 (461) 2892 (474) <0.001

NC, normal controls; MCI, mild cognitive impairment; AD, Alzheimer’s disease; MMSE, mini mental state examination; SD, standard deviation.