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. 2023 May 16;3(4):100332. doi: 10.1016/j.xops.2023.100332

Figure 2.

Figure 2

Morphological development of photoreceptors before postnatal day (P) 7 is not affected by phosphodiesterase 6 (PDE6G) depletion. Retinas were dissected from P7 Pde6g+/− (control) and Pde6g−/− (mutant) mice, sectioned, and immunolabeled. A, Representative images of sections stained for PDE6G and cone arrestin, PDE6B, or glutamic-acid-rich protein (GARP), and counterstained with Hoechst. B, Outer nuclear layer (ONL) thickness. Circles and squares, individual mice. Pde6g+/− (n = 3); Pde6g−/− (n = 5). Data are presented as the mean ± standard error of the mean and group means compared by an unpaired t test. Scale bar, 20 μm. INL = inner nuclear layer; ns = not significant; OS = outer segment.