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. 2023 May 16;3(4):100332. doi: 10.1016/j.xops.2023.100332

Figure 5.

Figure 5

Retinal blood vessel degeneration in Pde6g−/− mice. A, Retinal flatmounts were immunostained for isolectin GS-IB4. B, Quantification of deep vascular plexus (DVP) + intermediate vascular plexus (IVP) blood vessel in retinal center and periphery: postnatal day (P) 16 (n = 2–3), P30 (n = 3–4), and P44 (n = 5). C, Retinas from P44 mice were flat-mounted, trypsin digested, and hematoxylin–eosin stained. Data presented as mean ± standard error of the mean. D, Quantification of acellular capillaries: Pde6g+/− (n = 3–4) and Pde6g−/− (n = 3). Circles and squares, individual mice. Pde6g−/− vs. Pde6g+/− age-matched group means were compared by unpaired t tests. ∗P 0.02; ∗∗P 0.01; ∗∗∗P < 0.001. Scale bars, 50 μm.