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. 2023 May 16;3(4):100332. doi: 10.1016/j.xops.2023.100332

Figure 7.

Figure 7

Retinal pigment epithelium (RPE) remodeling in Pde6g−/− mice. RPE-choroid-sclera preparations from Pde6g+/− mice at postnatal day (P) 44 and Pde6g−/− mice at P16, P30, and P44 were flat-mounted, immunostained for β-catenin, images were taken in center and periphery, and Z-Stacks merged. A, Representative immunofluorescence images. Scale bar, 50 μm. B–F, Quantification of RPE cell parameters from P44 mice. Circles and squares, individual mice. N values for Pde6g+/− and Pde6g−/− mice, respectively: (B, D–F) 4–5 and 4; (C) 5 and 2–4. Data presented as mean ± standard error of the mean. Pde6g−/− vs. Pde6g+/− age-matched group means were compared by unpaired t tests. ∗P < 0.03; ∗∗P 0.01; ∗∗∗P < 0.001.