Abstract
Matched groups of patients suffering from Huntington's disease and Alzheimer's disease were compared for psychiatric morbidity prior to the onset of dementia. The Huntington's disease group showed twice the incidence of major affective disorder. This finding suggests a specific relationship between Huntington's disease and major affective disorder rather than the latter being a non-specific prodromal feature of dementia.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Breitner J. C., Folstein M. F. Familial Alzheimer Dementia: a prevalent disorder with specific clinical features. Psychol Med. 1984 Feb;14(1):63–80. doi: 10.1017/s0033291700003081. [DOI] [PubMed] [Google Scholar]
- Folstein S. E., Franz M. L., Jensen B. A., Chase G. A., Folstein M. F. Conduct disorder and affective disorder among the offspring of patients with Huntington's disease. Psychol Med. 1983 Feb;13(1):45–52. doi: 10.1017/s0033291700050054. [DOI] [PubMed] [Google Scholar]
- Folstein S., Abbott M. H., Chase G. A., Jensen B. A., Folstein M. F. The association of affective disorder with Huntington's disease in a case series and in families. Psychol Med. 1983 Aug;13(3):537–542. doi: 10.1017/s0033291700047966. [DOI] [PubMed] [Google Scholar]
- Koehler K., Sass H. Affective psychopathology in Huntington's disease: the Johns Hopkins hypothesis and German psychiatry. Psychol Med. 1984 Nov;14(4):733–737. doi: 10.1017/s0033291700019693. [DOI] [PubMed] [Google Scholar]