Table 1.

Integrins in chorioretinal diseases.

Disease	Integrin Type	Vitreoretinal location	Study
DR	β1	Retinal micro- vessels	Roth et al. Proc Natl Acad Sci USA, 1993. 90(20): p. 9640–9644
	αvβ3, αvβ5	FVM tissue	Friedlander, M., et al., Proc Natl Acad Sci U S A, 1996. 93 (18): p. 9764–9
	α5β1	Matrigel assay	Klein, S., et al. Molecular and cellular biology, 2002. 22(16): p. 5912–5922
	α1β1 and α2β1	Non-endothelial regions of FVM	Friedlander, M., et al., Proc Natl Acad Sci U S A, 1996. 93 (18): p. 9764–9
AMD	β5, αvβ5	Retina, RPE	Nandrot, E.F., et al., The Journal of experimental medicine, 2004. 200(12): p. 1539–1545
	αvβ3	Subretinal vascular cells	Friedlander, M., et al., Proc Natl Acad Sci U S A, 1996. 93 (18): p. 9764–9
	α5β1	CNV membranes	Ramakrishnan, V., et al. J Exp Ther Oncol, 2006. 5(4): p. 273–86

AMD, age-related macular degeneration; DR, diabetic retinopathy, FVM, fibrovascular membrane; RPE, retinal pigment epithelium