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. 2023 Jun 8;4:1193141. doi: 10.3389/falgy.2023.1193141

Table 3.

Association of parental TB with offspring asthma, stratified by parent's sex, offspring sex, and both parental and offspring's sex.

Current asthma ≥3 asthma symptoms Current asthma and/or ≥3 asthma symptoms
aOR (95% CI) P value aOR (95% CI) P value aOR (95% CI) P value
Parental lines
 Maternal 1.38 (1.01–1.90) 0.042 1.55 (1.17–2.07) 0.002 1.45 (1.12–1.88) 0.004
 Paternal 1.57 (1.12–2.19) 0.009 1.31 (0.95–1.82) 0.103 1.36 (1.02–1.81) 0.038
Offspring's sex
 Female 1.34 (0.99–1.80) 0.056 1.35 (1.02–1.77) 0.033 1.33 (1.03–1.70) 0.026
 Male 1.25 (0.81–1.94) 0.306 1.13 (0.75–1.71) 0.546 1.13 (0.79–1.61) 0.470
Parent-offspring sex
 Mother-daughter 1.36 (0.92–1.99) 0.119 1.55 (1.09–2.18) 0.014 1.43 (1.03–1.97) 0.030
 Mother-son 1.34 (0.77–2.33) 0.301 1.42 (0.85–2.37) 0.182 1.40 (0.90–2.17) 0.130
 Father-daughter 1.42 (0.93–2.16) 0.106 1.39 (0.94–2.05) 0.100 1.41 (0.99–2.01) 0.056
 Father-son 1.85 (1.07–3.21) 0.028 1.09 (0.59–2.01) 0.780 1.21 (0.74–2.01) 0.437

Model adjusted for parental education, parental smoking habits, parental asthma. aOR, adjusted odds ratio; CI, confidence interval.