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Structural origins of stabilizing ACE2/RBD interactions. Closeups of the ACE2(cyan)/RBD(pink) showing key interactions in wild-type (WT) and mutant proteins. Hydrophobic contacts are in grey, π-π interactions are in purple, hydrogen bonds are shown as black dashed lines, unsatisfied polar group of N501 is in cyan, favorable hydrophobic contact between T501 and Y41 in grey, and all distances are in Å.
