Optimization of the reaction conditions.

Entry	R	Ligand	Base	Yielda (%)
1b	Ph	SPhos	Et3N	3a, 77
2b	Ph	DavePhos	Et3N	3a, 92
3	Ph	DavePhos	Et3N	3a, 88
4c	Ph	DavePhos	Et3N	3a, 91 (82)d
5	CH2CH2OH	DavePhos	Et3N	5a, 34
6	CH2CH2OH	DavePhos	K3PO4	5a, 42
7	CH2CH2OH	SPhos	K3PO4	5a, 63
8b	CH2CH2OH	SPhos	K3PO4	5a, 54
9c	CH2CH2OH	SPhos	K3PO4	5a, 65 (58)d

^aNMR yields determined using trichloroethylene (1.0 equiv.) as internal standard.

^bWith CuI (5 mol %).

^cOn 0.4 mmol scale.

^dIsolated yield.