Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Apr 18;8(3):e00662-22. doi: 10.1128/msphere.00662-22

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Castro et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

PMC Copyright notice

FIG 2 — Total IgG antibody levels against Spike/RBD of SARS-CoV-2 after Sputnik V vaccination. The levels of IgG antibodies against the ectodomain of the original Wuhan spike protein and RBD were measured by COVIDAR IgG ELISA, and quantification was carried out calculating the PI values (range from 1 to 10) according to manufacturer’s instructions. (A) Serum samples were collected 2 weeks after application of the first dose (1D) (n = 122) and 1 to 2 weeks after second dose (2D) (n = 999) of Sputnik V. (B) Antibody levels were evaluated in 380 individuals after 2 and 24 weeks after completion of the vaccination schedule (wpv). (C) Individual evolution of total IgG anti-Spike/RBD levels at 2 and 24 wpv. Individual PI values and geometric mean with 95%CI are shown. Mann-Whitney U test was used for analysis of the total IgG antibody levels. Wilcoxon matched-pair test was used for individual longitudinal analysis of the total IgG antibody levels. Statistical significance is shown with the following notations: ****, P < 0.0001.