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. 2023 Apr 18;8(3):e00662-22. doi: 10.1128/msphere.00662-22

FIG 5.

FIG 5

Correlation between anti-S/RBD antibodies and neutralizing antibodies against ancestral SARS-CoV-2 after Sputnik V vaccination in naive individuals. Sera of 29 naive individuals collected at 2 and 24 weeks after completion of the vaccination schedule (wpv) with Sputnik V were used. (A) Correlation between IgG anti-S/RBD (PI) tested with COVIDAR and Anti-S/RBD antibodies tested with Elecsys Anti-SARS-CoV-2 S assay (Roche) (n = 56). Samples with PI of ≥10 were set at PI = 10, and samples with antibody titers above 250 U/mL were set at 250. (B) Correlation of NT with IgG anti-S/RBD (PI) tested with COVIDAR IgG (n = 58). Samples with PI of ≥10 were set at PI = 10. (C) Correlation of NT with anti-S/RBD antibody titers tested with Elecsys assay (Roche) (n = 56). Samples with antibody titers above 250 U/mL were set at 250. NT below 8 were set at 1. LOD indicates the limit of detection of neutralizing antibodies. Correlation was analyzed by Spearman’s r test. P < 0.05 was considered significant.