TABLE 2.
Factors associated with change in axillary surgery post-sentinel lymph node biopsy
*1401 patients had an Oncotype DX score available
SLNB sentinel lymph node biopsy, ALND axillary lymph node dissection, IDC invasive ductal carcinoma, ILC invasive lobular carcinoma
| Characteristic | SLNB only (n = 1766) |
ALND appropriate post-SLNB (n = 20) |
p-value |
|---|---|---|---|
| Median age at surgery, years | 62 | 58 | 0.3 |
| Tumor size | < 0.001 | ||
| < 5 mm | 240 (100%) | 0 (0%) | |
| 6-10 mm | 531 (99.8%) | 1 (0.2%) | |
| 11-20 mm | 714 (99%) | 8 (1%) | |
| 21-30 mm | 214 (97%) | 7 (3%) | |
| 31-50 mm | 62 (94%) | 4 (6%) | |
| > 50 mm | 5 (100%) | 0 (0%) | |
| Tumor differentiation | 0.3 | ||
| Well | 380 (99.7%) | 1 (0.3%) | |
| Moderately | 1084 (99%) | 15 (1%) | |
| Poorly | 302 (99%) | 4 (1%) | |
| Histology | 0.2 | ||
| IDC | 1407 (99%) | 14 (1%) | |
| ILC | 227 (99%) | 3 (1%) | |
| Mixed | 95 (99%) | 1 (1%) | |
| Other | 37 (95%) | 2 (5%) | |
| Oncotype DX Recurrence Score* | > 0.9 | ||
| ≤ 25 | 1179 (99.7) | 3 (0.3%) | |
| > 25 | 219 (100%) | 0 (0%) |