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. Author manuscript; available in PMC: 2024 Apr 1.
Published in final edited form as: Gene Ther. 2022 Jan 8;30(3-4):222–231. doi: 10.1038/s41434-021-00307-0

Figure 6. CD19-CAR(Mem) and standard CD19-CAR T cells have comparable antitumor activity in vivo.

Figure 6.

CD19-CAR(Mem) and standard CD19-CAR T cells were generated from two donors (A-D) E20003 and (E-H) E19028 and evaluated in BV173.ffluc xenograft NSG mouse model (n=5 per group). Non-transduced (NT) memory or standard T cells served as control. (B, F) Bioluminescence images. (C, G) Quantification of bioluminescence signal; n=5 per group, Two-way ANOVA, *P<0.05, ***P<0.001, ****P<0.0001. (D, H) Kaplan-Meier survival analysis, Log-rank test, *P<0.05, **P<0.01.