Table 1. Demographic and clinical features of the individuals with a hospital admission in SUS or an emergency care consultation in the ECDS dataset for myocarditis and pericarditis: data from entire eligible population in England.
person years | SUS pericarditis case count = 1,651* | SUS pericarditis risk per 100,000 | SUS myocarditis case count = 2,284* | SUS myocarditis risk per 100,000 | ECDS pericarditis case count = 6,461 | ECDS pericarditis risk per 100,000 | ECDS myocarditis case count = 1,472 | ECDS myocarditis risk per 100,000 | ||
---|---|---|---|---|---|---|---|---|---|---|
Age group | 12 to 15 | 2,742,347 | 8 | 0.29 | 28 | 1.02 | 111 | 4.05 | 42 | 1.53 |
16 to 17 | 1,305,334 | 30 | 2.30 | 73 | 5.59 | 151 | 11.57 | 71 | 5.44 | |
18 to 19 | 1,296,676 | 54 | 4.16 | 119 | 9.18 | 241 | 18.59 | 118 | 9.10 | |
20 to 24 | 3,730,389 | 119 | 3.19 | 233 | 6.25 | 757 | 20.29 | 241 | 6.46 | |
25 to 29 | 4,196,722 | 117 | 2.79 | 199 | 4.74 | 754 | 17.97 | 184 | 4.38 | |
30 to 34 | 4,513,956 | 127 | 2.81 | 200 | 4.43 | 715 | 15.84 | 163 | 3.61 | |
35 to 39 | 4,297,665 | 106 | 2.47 | 166 | 3.86 | 705 | 16.40 | 144 | 3.35 | |
40 to 44 | 3,956,356 | 126 | 3.18 | 153 | 3.87 | 565 | 14.28 | 91 | 2.30 | |
45 to 49 | 3,768,292 | 131 | 3.48 | 155 | 4.11 | 517 | 13.72 | 84 | 2.23 | |
50 to 54 | 4,013,470 | 140 | 3.49 | 157 | 3.91 | 486 | 12.11 | 61 | 1.52 | |
55 to 59 | 3,903,178 | 139 | 3.56 | 166 | 4.25 | 431 | 11.04 | 74 | 1.90 | |
60 to 64 | 3,320,364 | 124 | 3.73 | 145 | 4.37 | 293 | 8.82 | 57 | 1.72 | |
65 to 69 | 2,773,874 | 111 | 4.00 | 113 | 4.07 | 242 | 8.72 | 45 | 1.62 | |
70 to 74 | 2,732,488 | 125 | 4.57 | 122 | 4.46 | 191 | 6.99 | 36 | 1.32 | |
75 to 79 | 2,069,915 | 82 | 3.96 | 101 | 4.88 | 146 | 7.05 | 31 | 1.50 | |
80 to 84 | 1,390,802 | 61 | 4.39 | 91 | 6.54 | 83 | 5.97 | 17 | 1.22 | |
85 to 89 | 868,675 | 39 | 4.49 | 44 | 5.07 | 55 | 6.33 | 10 | 1.15 | |
90+ | 504,934 | 12 | 2.38 | 19 | 3.76 | 18 | 3.56 | 3 | 0.59 | |
Sex | Male | 25,717,812 | 1,132 | 4.40 | 1,456 | 5.66 | 4,634 | 18.02 | 1,001 | 3.89 |
Female | 25,667,624 | 519 | 2.02 | 828 | 3.23 | 1,827 | 7.12 | 471 | 1.83 | |
Region | East of England | 5,910,664 | 175 | 2.96 | 335 | 5.67 | 703 | 11.89 | 165 | 2.79 |
London | 8,807,901 | 249 | 2.83 | 420 | 4.77 | 973 | 11.05 | 239 | 2.71 | |
Midlands | 9,496,410 | 220 | 2.32 | 321 | 3.38 | 986 | 10.38 | 248 | 2.61 | |
North East and Yorkshire | 7,641,777 | 217 | 2.84 | 273 | 3.57 | 938 | 12.27 | 186 | 2.43 | |
North West | 6,393,140 | 215 | 3.36 | 278 | 4.35 | 713 | 11.15 | 199 | 3.11 | |
South East | 8,025,838 | 365 | 4.55 | 445 | 5.54 | 1,230 | 15.33 | 267 | 3.33 | |
South West | 5,109,705 | 210 | 4.11 | 212 | 4.15 | 859 | 16.81 | 153 | 2.99 | |
Ethnicity | Asian | 4,398,660 | 94 | 2.14 | 155 | 3.52 | 513 | 11.66 | 103 | 2.34 |
Black, African, Caribbean | 1,756,382 | 108 | 6.15 | 133 | 7.57 | 468 | 26.65 | 95 | 5.41 | |
Mixed, Multiple | 820,496 | 22 | 2.68 | 45 | 5.48 | 145 | 17.67 | 38 | 4.63 | |
NK | 6,752,624 | 95 | 1.41 | 182 | 2.70 | 448 | 6.63 | 101 | 1.50 | |
Other | 1,173,462 | 42 | 3.58 | 69 | 5.88 | 165 | 14.06 | 48 | 4.09 | |
White | 36,483,810 | 1,290 | 3.54 | 1,700 | 4.66 | 4,722 | 12.94 | 1,087 | 2.98 | |
Clinically vulnerable | No | 47,787,906 | 1,387 | 2.90 | 1,943 | 4.07 | 5,830 | 12.20 | 1,333 | 2.79 |
Yes | 3,597,530 | 264 | 7.34 | 341 | 9.48 | 631 | 17.54 | 139 | 3.86 | |
In an “at risk” group | No | 43,400,928 | 1,107 | 2.55 | 1,446 | 3.33 | 4,545 | 10.47 | 1,010 | 2.33 |
Yes | 7,984,508 | 544 | 6.81 | 838 | 10.50 | 1,916 | 24.00 | 462 | 5.79 | |
Unvaccinated | 16,751,085 | 206 | 1.23 | 340 | 2.03 | 1,036 | 6.18 | 225 | 1.34 | |
Primary course | ChAdOx1 | 18,381,521 | 728 | 3.96 | 859 | 4.67 | 2,332 | 12.69 | 439 | 2.39 |
BNT162b2 | 15,459,412 | 670 | 4.33 | 972 | 6.29 | 2,833 | 18.33 | 728 | 4.71 | |
mRNA-1273 | 793,417 | 47 | 5.92 | 112 | 14.12 | 259 | 32.64 | 79 | 9.96 |
*Eleven SUS cases had a diagnosis of both myocarditis and pericarditis.
ECDS, Emergency Care Data Set; SUS, Secondary Uses Service.