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. 2023 Jun 7;20(6):e1004245. doi: 10.1371/journal.pmed.1004245

Table 3. RI of infection by the SCCS method (adjusted for time period (4 weekly period)) for hospital admitted patients with myocarditis or pericarditis aged 12+ years who tested positive for SARS-CoV-2 infection.

Interval from test to admission Type of infection Vaccination status Variant
First Reinfection Unvaccinated^ Vaccinated ≥1 dose Alpha Delta Omicron
Day 0
 Number cases 50 4 19 35 3 29 22
 Person years 3.1 0.9 1 3.1 0.3 2.3 1.4
 RI (95% CIs) 17.29 4.75 24.66 11.98 13.96 13.18 16.79
(12.96, 23.00) (1.77, 12.80) (15.42, 39.44) (8.39, 16.59) (4.37, 46.64) (9.06, 19.17) (10.83, 26.01)
p < 0.001 p = 0.002 p < 0.001 p < 0.001 p < 0.001 p < 0.001 p < 0.001
Days 1–27
 Number cases 193 50 71 172 27 150 66
 Person years 82.4 22.5 27 77.8 10.8 62.1 32
 RI (95% CIs) 2.57 2.49 3.32 2.33 3.13 2.58 2.34
(2.19, 3.01) (1.82, 3.41) (2.54, 4.33) (1.96, 2.76) (2.02, 4.84) (2.15, 3.1) (1.77, 3.1)
p < 0.001 p < 0.001 p < 0.001 p < 0.001 p < 0.001 p < 0.001 p < 0.001

^ Includes infections before the first dose.

CI, confidence interval; RI, relative incidence; SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus 2; SCCS, self-controlled case series.