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. 2023 Jun 7;20(6):e1004245. doi: 10.1371/journal.pmed.1004245

Table 4. Attributable risk estimates with 95% CIs for an admission for myocarditis; exposures with elevated RIs with p < 0.001 0–6 days post-vaccine and 0 to 27 days post a laboratory confirmed SARS-CoV-2 in the SCCS analysis using the dataset that includes infections in unvaccinated individuals.

Vaccine exposure Admissions in risk period RI Attributable fraction Attributable cases Doses Attributable risk per million vaccinations (95% CI)
0 to 6 days before admission 16 to 39 year olds
Dose 1 ChAdOx1 9 5.23 0.809 7.3 2,099,584 3.5 (2.6,3.9)
Dose 1 BNT162b2 18 2.23 0.552 9.9 9,705,976 1.02 (0.5,1.3)
Dose 2 BNT162b2 40 5.34 0.813 32.5 9,519,878 3.4 (3.1,3.6)
Booster BNT 162b2 17 4.38 0.772 13.1 5,319,875 2.5 (2.0,2.8)
Dose 1 mRNA 1273 8 8.69 0.885 7.1 1,023,825 6.9 (5.9,7.4)
Dose 2 mRNA 1273 38 56.48 0.982 37.3 881,058 42.4 (41.9,42.7)
Booster mRNA 1273 11 7.88 0.873 9.6 2,144,219 4.5 (3.9,4.8)
Vaccine exposure Admissions in risk period RI Attributable fraction Attributable cases Doses Attributable risk per million vaccinations (95% CI)
0 to 6 days before admission all 16+ year olds
Dose 2 BNT162b2: males 40 4.42 0.774 31.0 8,734,711 3.5 (3.1,3.8)
Dose 1 mRNA 1273: males 9 10.48 0.905 8.1 747,072 10.9 (9.6,11.5)
Dose 2 mRNA 1273: males 35 58.24 0.983 34.4 625,871 55.0 (54.3,55.3)
Booster mRNA 1273: males 12 3.8 0.737 8.8 3,539,697 2.5 (1.7,2.9)
Dose 2 mRNA 1273: females 4 23.26 0.957 3.8 498,121 7.7 (6.8,7.9)
SARS-CoV-2 infection 0–27 days before admission Admissions in risk period RI Attributable fraction Attributable cases Cases Attributable risk per million infections
16 to 39 year olds day 0 15 6.98 0.857 12.9 8,398,257 1.5 (1.4–1.6)
≥40 year olds day 0 37 23.56 0.958 35.4 6,570,699 5.4 (5.6, 5.5)
16–39 year olds days 1–27 113 2.09 0.522 58.9 8,398,257 7.0 (5.5, 8.3)
≥40 year olds days 1–27 124 3.07 0.674 83.6 6,570,699 12.7 (11.3, 13.9)

CI, confidence interval; RI, relative incidence; SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus 2; SCCS, self-controlled case series.