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Treatment of cryptococcus
| CNS disease disseminated disease severe pulmonary disease | Asymptomatic or mild-moderate pulmonary disease | |
|---|---|---|
| Induction | Liposomal Amphotericin B: 3–4 mg/kg/d Amphotericin B lipid complex: 5 mg/kg/d + Flucytosine 25 mg/kg PO q6h Duration: minimum 2 wk |
— |
| Consolidation | Fluconazole: 400–800 mg/d Duration: 8 wk |
— |
| Maintenance | Fluconazole: 200–400 mg/d Duration: 6–12 mo |
Fluconazole: 400 mg/d Duration: 6–12 mo |
Abbreviation: CNS, central nervous system.
