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. 2023 Jun 8;14:1161067. doi: 10.3389/fimmu.2023.1161067

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Copyright © 2023 Carlini, Noonan, Abdalalem, Goletti, Sansone, Calabrone and Albini

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Potential role of IL-10 in counteracting ACE2 downregulation, rebalancing RAAS system and mitigating tissue damage caused by SARS-CoV-2 in severe COVID-19 and Long COVID syndrome.