Figure 5. Effect TPMPA on EtOH inhibition of evoked dopamine release ex vivo.
(A) Representative example of the effects of the of the Rho-1 subunit antagonist TPMPA (10 μM) on evoked DA release in the NAc ex vivo. Insets show representative superimposed I vs t and I vs V plots before and after TPMPA and EtOH. (B) Summary of TPMPA on 80 mM EtOH inhibition of evoked DA release. Values in parentheses represent n values. Values in parentheses represent n values. Asterisks *** indicate significance level p<0.001.