Skip to main content
. Author manuscript; available in PMC: 2024 Jan 11.
Published in final edited form as: J Am Chem Soc. 2022 Dec 22;145(1):78–88. doi: 10.1021/jacs.2c07504

Figure 6.

Figure 6.

Spectra (A) and a calibration curve (B) of mouse blood with various COHb levels determined by 10 mM CODP-102 (λEX = 395 nm); (C) blood COHb levels of mice dosed with or without AC-306 (50 mg/kg) determined with CODP-102 and a CO-oximeter; (D) blood COHb levels of mice dosed with or without CO-306 (200 mg/kg) determined with CODP-103 and a CO-oximeter; (E) relative CO levels of HeLa cells treated with 0.3 μM CDDO-Me (6 h) or 250 ppm CO gas (2 h); (E) Western blot of HO-1 in HeLa cells treated with 0.3 μM CDDO-Me (6 h), β-actin was probed as the loading control. For C-D, results shown as average ± SD (n=3), ****P<0.0001, ns: not significant (P>0.05), t-test.