Table 1.
Dental anomalies reported in OFC syndromes
| Anomaly | 22q11 | SATB2 | Kabuki | ODD | EEC | VWS | MSX1 | HPE | ANKRD11 |
|---|---|---|---|---|---|---|---|---|---|
| Neonatal teeth | - | - | + | - | - | + | - | - | - |
| Delayed tooth eruption | + | - | - | - | - | - | - | - | - |
| Premature loss | - | - | - | + | - | - | - | - | - |
| Oligodontia | + | + | + | + | + | + | + | + | + |
| Abnormally shaped teeth | + | + | + | - | + | - | - | - | + |
| Irregular/crowded teeth | + | + | - | - | - | - | - | + | - |
| Small teeth | - | - | - | + | + | - | - | - | - |
| Malocclusion | - | + | - | - | - | - | - | - | - |
| Enamel abnormalities | + | - | - | + | + | - | - | - | + |
| Single central incisor | + | - | - | - | - | - | - | + | - |
| Macrodontia | - | - | - | - | - | - | - | - | + |
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Key: 22q11 = DiGeorge syndrome or velocardiofacial syndrome SATB2 = SATB2-associated disorder or Glass syndrome ODD = Oculo-dento-digital syndrome EEC = Ectrodactyly-ectodermal dysplasia clefting VWS = Van der Woude syndrome HPE = Holoprosencephaly ANKRD11 = Gene causing KBG syndrome | |||||||||