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Serum α-synuclein IP/RT-QuIC results and α-synuclein IP/RT-QuIC assay characteristics per diagnosis
| Diagnosis | n | IP/RT-QuIC results +/− | Positive results |
|---|---|---|---|
| Synucleinopathies | |||
| PD | 221 | 210/11 | 95% |
| MSA | 39 | 25/14 | 64% |
| DLB | 10 | 9/1 | 90% |
| RBD | 9 | 4/5 | 44% |
| Non-synucleinopathies | |||
| PSP | 30 | 1/29 | 3% |
| AD | 25 | 4/21 | 16% |
| PRKN | 17 | 0/17 | 0% |
| Controls | 128 | 11/117 | 8.5% |
Data are presented as numbers. n, number of participants who received IP/RT-QuIC.
