Table 3.

Model performances measured by iAUC in the overall survival prediction

Model	iAUC	95% CI	iAUC difference	95% CI	p
Lung 1 training set
Radiomics	0.615	0.584–0.646
Clinical	0.549	0.511–0.587
Radiomics + clinical	0.621	0.588–0.654
Radiomics + clinical vs. radiomics			0.006	−0.019–0.032	0.657
Radiomics + clinical vs. clinical			0.072	0.037–0.107	< 0.001***
Radiomics vs. clinical			0.066	0.016–0.116	0.0082**
Lung 2 testing set
Radiomics	0.586	0.493–0.679
Clinical	0.687	0.600–0.775
Radiomics + clinical	0.736	0.654–0.819
Radiomics + clinical vs. radiomics			0.150	0.055–0.245	0.0018**
Radiomics + clinical vs. clinical			0.049	−0.009–0.106	0.09
Radiomics vs. clinical			−0.101	−0.239–0.036	0.149
Kidney external validation set
Radiomics	0.719	0.598–0.84
Clinical	0.761	0.621–0.901
Radiomics + clinical	0.834	0.722–0.946
Radiomics + clinical vs. radiomics			0.116	0.004–0.227	0.041 *
Radiomics + clinical vs. clinical			0.073	−0.018–0.165	0.12
Radiomics vs. clinical			−0.042	−0.209–0.125	0.634
Head & neck external validation set
Radiomics	0.643	0.563–0.722
Clinical	0.693	0.614–0.771
Radiomics + clinical	0.732	0.655–0.809
Radiomics + clinical vs. radiomics			0.089	0.016–0.163	0.016*
Radiomics + clinical vs. clinical			0.039	−0.013–0.091	0.149
Radiomics vs. clinical			−0.05	−0.151–0.051	0.331