Table 5.

Top CpG sites associated with the plaque density

Chr	Pos	Probe	Islands_name	Relationship to gene	Symbol	Beta (regression)	Δβ	p	BH	Rank (diff. analysis)
8	41,519,399	cg11823178		Body; TSS1500	ANK1; MIR486	0.168	0.023	6.7E-16	2.3E-12	1
8	41,519,308	cg05066959		Body; TSS1500	ANK1; MIR486	0.172	0.039	8.7E-16	2.3E-12	2
17	1,373,605	cg05417607	chr17:1,375,216–1,375,460	Body	MYO1C	0.141	0.020	2.6E-15	4.6E-12	7
17	72,779,428	cg22312249		Body	TMEM104	0.097	0.026	5.5E-15	6.3E-12	12
15	74,836,094	cg19144497	chr15:74,833,241–74,833,961	5’UTR	ARID3B	0.086	0.038	6.0E-15	6.3E-12	16
8	119,122,430	cg05313153	chr8:119,123,974–119,124,432	1stExon	EXT1	0.078	0.021	2.0E-14	1.8E-11	3
3	182,968,758	cg14761246	chr3:182,971,429–182,972,635	Body	MCF2L2	0.122	0.022	6.8E-14	5.1E-11	40
3	188,664,632	cg12307200	chr3:188,665,275–188,665,552			− 0.091	− 0.021	5.3E-13	3.5E-10	5
10	73,472,315	cg07571519		3’UTR; Body	C10orf105; CDH23	0.073	0.020	7.6E-13	4.4E-10	22
10	77,188,318	cg18456331	chr10:77,191,061–77,191,571			0.117	0.027	9.2E-13	4.8E-10	146
10	112,260,509	cg02927679	chr10:112,257,163–112,258,684	Body	DUSP5	0.090	0.029	1.4E-12	6.7E-10	253
3	36,782,467	cg21113478		TSS1500	DCLK3	0.090	0.027	2.8E-12	1.2E-09	242
12	9,265,989	cg08300930		Body	A2M	0.061	0.018	7.3E-12	2.9E-09	185
1	65,531,864	cg13390284	chr1:65,532,161–65,533,212			0.105	0.038	1.2E-11	4.5E-09	131
13	40,396,777	cg16042652				0.101	0.028	1.5E-11	4.9E-09	145
15	42,652,294	cg14833933		1stExon	CAPN3	0.074	0.030	1.5E-11	4.9E-09	576
6	16,758,889	cg00464814	chr6:16,760,178–16,762,985	5’UTR	ATXN1	0.095	0.023	2.4E-11	7.2E-09	738
10	22,603,999	cg10713515	chr10:22,604,907–22,605,632	TSS1500	COMMD3	0.068	0.019	2.5E-11	7.2E-09	8
17	32,741,121	cg20942162				0.071	0.026	3.1E-11	8.6E-09	78
21	47,855,893	cg23449541	chr21:47,855,892–47,856,143	Body	PCNT	0.092	0.021	3.3E-11	8.6E-09	15
8	42,033,472	cg17693222		3’UTR	PLAT	0.054	0.013	3.4E-11	8.6E-09	4
6	79,911,416	cg22032366		Body	HMGN3	0.107	0.032	4.0E-11	9.6E-09	329