Table 2.
Co-reported MedDRA terms mentioned in at least ten reports
| Co-reported preferred terms (MedDRA) | Number of reports (%) |
|---|---|
| Cytokine release syndrome | 154 (68.8) |
| Pyrexia | 85 (37.9) |
| Neurotoxicity | 72 (32.1) |
| Hypotension | 69 (30.8) |
| Hypoxia | 46 (20.5) |
| Immune effector cell-associated neurotoxicity syndrome | 45 (20.1) |
| Encephalopathy | 43 (19.2) |
| Multiple organ dysfunction syndrome | 38 (17.0) |
| Respiratory failure | 33 (14.7) |
| Thrombocytopenia | 32 (14.3) |
| Tachycardia | 31 (13.8) |
| Neutropenia | 29 (12.9) |
| Cytopenia | 28 (12.5) |
| Malignant neoplasm progression | 26 (11.6) |
| Sepsis | 25 (11.2) |
| Confusional state | 22 (9.8) |
| Coagulopathy | 21 (9.4) |
| Fatigue | 21 (9.4) |
| Disseminated intravascular coagulation | 20 (8.9) |
| Pancytopenia | 19 (8.5) |
| Hemophagocytic lymphohistiocytosis | 19 (8.5) |
| Pleural effusion | 18 (8.0) |
| Somnolence | 18 (8.0) |
| Atrial fibrillation | 17 (7.6) |
| Febrile neutropenia | 17 (7.6) |
| Hypogammaglobulinemia | 17 (7.6) |
| Platelet count decreased | 17 (7.6) |
| White blood cell count decreased | 17 (7.6) |
| Hemoglobin decreased | 16 (7.1) |
| Acute respiratory failure | 15 (6.7) |
| Death | 15 (6.7) |
| Diffuse large B-cell lymphoma | 15 (6.7) |
| Depressed level of consciousness | 14 (6.3) |
| Tachypnea | 14 (6.3) |
| Tremor | 14 (6.3) |
| Agitation | 13 (5.8) |
| Aphasia | 13 (5.8) |
| Blood creatinine increased | 13 (5.8) |
| Hepatic failure | 13 (5.8) |
| Hepatotoxicity | 13 (5.8) |
| Seizure | 13 (5.8) |
| Mental status changes | 13 (5.8) |
| Anemia | 12 (5.4) |
| Dyspnea | 12 (5.4) |
| Hypertension | 12 (5.4) |
| Neutrophil count decreased | 12 (5.4) |
| Septic shock | 12 (5.4) |
| Serum ferritin increased | 12 (5.4) |
| Acute lymphocytic leukemia recurrent | 12 (5.4) |
| Infection | 11 (4.9) |
| Tumor lysis syndrome | 11 (4.9) |
| Candida infection | 11 (4.9) |
| Cardiac arrest | 10 (4.5) |
| Delirium | 10 (4.5) |
| Hematocrit decreased | 10 (4.5) |
| Headache | 10 (4.5) |
| Hypervolemia | 10 (4.5) |
| Lactic acidosis | 10 (4.5) |
| Transaminases increased | 10 (4.5) |
| Staphylococcal infection | 10 (4.5) |
| Pulmonary toxicity | 10 (4.5) |