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. 2023 May 11;37(4):521–530. doi: 10.1007/s40259-023-00599-1

Table 3.

Comparison between reports of acute renal failure involving CAR-T cells, with and without cytokine release syndrome (CRS)

Overall With CRS Without CRS
Number of reports (%) 224 (100) 154 (68.8) 70 (31.3)
Male (%) 137 (61.2) 87 (58.4) 50 (75.8)
Median age, years (IQR) 60 (27–70) 57 (20–70) 60 (44–68)
Median time to onset, days 7 (3–18) 4 (3–8) 15 (6–146)
Outcome
  Fatal cases (%) 121 (54.0) 89 (57.8) 32 (45.7)
  Life-threatening reaction (%) 64 (28.6) 55 (35.7) 9 (12.9)
  Others (%) 39 (17.4) 10 (6.5) 29 (41.4)