Table 2:
Characteristics of Patients Achieving HBsAg Loss
ID | Treatment | Age in years | Sex | Race | HBeAg at Start of Treatment | Geno type | HBV DNA log10 IU/mL | qHBsAg log10 IU/mL | qHBeAg log10 IU/mL | ALT U/L | ISHAK | Week of HBsAg Loss | Status at time of HBsAg Loss |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
A | TDF alone | 66·7 | F | White | Positive | A2 | 8·6 | 5·1 | 3·6 | 129 | 2 | 71 | On treatment |
B | TDF alone | 45·9 | M | Black | Positive | A2 | 7·3 | 4·1 | 2·2 | 94 | 3 | 217 | Off treatment |
C | TDF alone | 41·2 | M | White | Positive | A2 | 8·6 | 5·0 | 3·4 | 92 | 6 | 197 | On treatment |
D | TDF alone | 37·5 | M | White | Positive | A2 | 8·8 | 4·9 | 3·2 | 66 | 2 | 217 | Off treatment |
E | TDF+PegIFN | 37·2 | F | Asian | Negative | C | 4·2 | 2·3 | N/A | 91 | 0 | 71 | On treatment |
F | TDF+PegIFN | 53·2 | M | White | Positive | A2 | 8·4 | 5·2 | 3·4 | 88 | 4 | 25 | On treatment |
G | TDF+PegIFN | 60·0 | M | White | Positive | A2 | 8·5 | 5·1 | 3·2 | 66 | 2 | 36 | On treatment |
H | TDF+PegIFN | 53·3 | F | Black | Positive | A2 | 8·4 | 4·8 | 3·5 | 54 | 5 | 25 | On treatment |
I | TDF+PegIFN | 34·4 | F | Asian | Positive | B | 8·1 | 4·5 | 3·3 | 56 | 1 | 121 | On treatment |
ALT, alanine aminotransferase; HAI, hepatitis activity index; PegIFN, peginterferon; TDF, tenofovir disoproxil fumarate