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. Author manuscript; available in PMC: 2024 Jul 1.
Published in final edited form as: Pharmacotherapy. 2023 Jan 5;43(7):588–595. doi: 10.1002/phar.2755

Table 3.

Most Common Co-Prescribed Chronic Medication Classes

No Documented Obesity
Medication Class 1 Medication Class 2 N %
Hypotensive Agents Stimulants 67020 12.0
Antihistamines Leukotriene Modifiers 38547 6.9
Antidepressants Stimulants 38279 6.9
Antihistamines Anti-inflammatory Agents (ENT) 36791 6.6
Antihistamines Stimulants 33856 6.1
Hypotensive Agents Antidepressants 29799 5.3
Adrenals Antihistamines 28488 5.1
Antipsychotics Stimulants 26431 4.7
Adrenals Leukotriene Modifiers 25997 4.7
Adrenals Sympathomimetic Agents 25212 4.5
Documented Obesity
Medication Class 1 Medication Class 2 N %
Antihistamines Anti-inflammatory Agents (ENT) 8737 11.3
Antihistamines Leukotriene Modifiers 7837 10.2
Hypotensive Agents Stimulants 7344 9.5
Adrenals Antihistamines 6467 8.4
Antidepressants Stimulants 6171 8.0
Adrenals Leukotriene Modifiers 5665 7.3
Antihistamines Sympathomimetic Agents 5580 7.2
Hypotensive Agents Antidepressants 5495 7.1
Adrenals Sympathomimetic Agents 5411 7.0
Antidepressants Antipsychotics 5331 6.9

Common examples of drugs in each class: Stimulants (methylphenidate); Leukotriene modifiers (montelukast); Hypotensive agents (clonidine); Antihistamines (cetirizine); Antidepressants (sertraline); Sympathomimetic agents (albuterol, pseudoephedrine); Adrenals (budesonide, other steroids); Anti-inflammatory agents ENT (fluticasone); Antipsychotics (risperidone); Anticonvulsants (levetiracetam)