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. 2023 Mar 23;51(11):5364–5376. doi: 10.1093/nar/gkad207

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© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — The statistics of human ZFPs and currently identified short motifs of ZFY and its orthologs. (A) Distribution of C2H2-type zinc finger proteins (ZFPs) in human genome. (B) Currently identified motif length vs. the number of fingers within each ZFP. (C) Contact residues of Zinc Finger Y (ZFY) and its close orthlogs, mZFY1, mZFY2 and ZFX. (D) Predicted motif by B1H method. (E) Motif of mouse ZFX identified by protein binding microarray (PBM); (F) Motif of mouse ZFX identified by ChIP-seq. (G,H) Motifs of human ZFY and mouse ZFY1 identified by Affinity-seq in this work respectively.