Table 2.

Possible patient selection considerations for CNA in different conditions

Condition	Patient considerations
Vasovagal syncope	•Cardioinhibitory response to tilt table testing (type 1, 2A, or 2B) •Significant and persistent debilitating symptoms that are refractory to conservative strategies such as physical countermeasures and exercise and medications •Shared decision-making process that discusses alternatives and the current limited evidence base for CNA
Functional AV block	•Younger (<50 years of age) •Periods of symptomatic AV block associated with hypervagotonia in whom permanent pacing is being considered for treatment. •Atropine restores AV conduction •No associated structural heart disease or other disorder associated with AV block (eg, metabolic, infectious, genetic causes) •Shared decision-making process that discusses alternatives and the current limited evidence base for CNA •Electrophysiology study confirms an intact conduction system and the absence of intra/infra-His disease.
Functional sinus bradycardia	•Younger (<50 years of age) •Periods of symptomatic sinus bradycardia associated with hypervagotonia in whom permanent pacing is being considered for treatment •Intrinsic sinus node disease is not present •Shared decision making process that discusses alternatives and the current limited evidence base for CNA

AV = atrioventricular; CNA = cardioneuroablation.