Table 1.
Prenatal alcohol exposure paradigm outcomes.
| Saccharin control | 5% ethanol group | |
|---|---|---|
| Daily 4 h 5% ethanol consumption | NA | 1.96 ± 0.06a (23) |
| Maternal serum ethanol concentration | NA | 25.1 ± 3.3b (14) |
| Maternal weight gain during pregnancy | 110.8 ± 2.3c (25) | 102.5 ± 3.1* (23) |
| Litter size | 11.1 ± 0.5d (25) | 11.0 ± 0.4 (23) |
| Pup birth weight | 8.22 ± 0.32e (25) | 7.95 ± 0.27 (23) |
a
Mean ± S.E.M. grams ethanol consumed/kg body weight/day.
b
Mean ± S.E.M. mg ethanol/dL in serum. Serum samples were collected 2 h after the introduction of the drinking tubes from a separate set of rat dams. This time point is at or near the peak blood ethanol concentration as ethanol consumption reduces significantly in the third and fourth hours of the drinking session (Davies et al., 2023).
c
Mean ± S.E.M. grams increase in body weight from GD 1 through GD 21. Asterisk denotes maternal weight gain data significantly less than control rats (t = 2.10, p = 0.042).
d
Mean ± S.E.M. number of live births/litter.
e
Mean ± S.E.M. grams pup birth weight.
NA, not applicable, (n)-Group sample.