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. 2023 Jun 9;10:1211797. doi: 10.3389/fnut.2023.1211797

Table 1.

Characteristics of the included studies on the association between consumption of ultra-processed food and risk of metabolic syndrome.

References Study design Country Sample size Follow-up (years) Mean age/age range Exposure assessment Outcome Effect sizes OR/RR (95%CI) Study quality Adjustment
Magalhães et al. (3) Cohort Brazil 896 12–16 y 37–39 y FFQ MetS 1.00 (0.99–1.01) 8 Sex, skin color, age, education, marital status, family income, alcohol consumption, smoking, level of physical activity and total caloric intake
Pan et al. (23) Cohort China 5,147 29 ≥18 y 24-h dietary recall MetS 1.17 (1.01–1.35) 9 Gender, age, education level, place of residence, regions, income level, smoking history, drinking status, metabolic equivalents, urbanicity, BMI, total energy intake, protein intake, fat intake, carbohydrate intake, and sodium intake
Barbosa et al. (24) Cross-sectional Brazil 895 - 19–55 y 24-h dietary recall MetS 1.09 (0.89–1.32) 7 Age, race/skincolor, marital status, schooling, family participation in a government program, family income, employment status, food insecurity, smoking and health problems in the last 15 days, excess weight and neck circumference
Canhada et al. (25) Cohort Brazil 8,065 8 y 35–74 y FFQ MetS 1.19 (1.07–1.32) 9 Age, sex, center, race or color, income, school achievement, smoking, physical activity, alcohol, energy intake, and BMI
Tavares et al. (26) Cross-sectional Brazil 210 - 12–19 y FFQ MetS 2.49 (1.24–3.57) 6 Smoking, family hypertriacylglycerolaemia and energy intake
Martínez Steele et al. (27) Cross-sectional USA 6,385 - ≥20 y 24-h dietary recall MetS 1.20 (1.07–1.35) 7 Sex, age group, race/ethnicity, ratio of family income to poverty and educational attainment, smoking status, physical activity, BMI (continuous).
Lavigne-Robichaud et al. (28) Cross-sectional Canada 811 - ≥18 y 24-h dietary recall MetS 1.90 (1.14–3.17) 7 Age (continuous), sex, area of residence (coastal/inland), current smoker (yes/no), alcohol drinker (yes/no, except for the aHEI- 2010 model) and total dietary energy intake (kcal/d, continuous)
Ivancovsky-Wajcman et al. (29) Cross-sectional Israel 789 - 40–70 y FFQ MetS 1.88 (1.31–2.71) 7 Age, gender, BMI, saturate fatty acids and protein intake (% of total kcal), physical activity (hours/week), coffee (cups/day) and fibers (g/day)
Nasreddine et al. (30) Cross-sectional Lebanon 302 - ≥18 y FFQ MetS 1.11 (0.26–4.65) 6 Age, gender, marital status, area of residence, level of education, income, smoking status, physical activity, total energy intake and BMI.

USA, United States; CVD, cardiovascular disease; BMI, Body mass index; DGAI, Dietary Guidelines Adherence Score; WC, Waist circumference.

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