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Rational design of biomaterials to activate DCs. Tailoring the properties of biomaterials is an important strategy for the design of immune adjuvants. Current studies illustrate that the properties of biomaterials, such as targeting ligands, size, morphology, surface charge and mechanical properties, need to be considered in the regulation of the DC‐mediated antitumor vaccination cascades. Rational modification and design of biomaterials can improve DC activation.
