Fig. 6.

Unveiling the age-sensitive contribution of microglia/infiltrating macrophages to poststroke repair processes. (A) Overview of age-sensitive alterations in repair-related inferred interactions between MG/MΦ and EC/OL/OPCs in poststroke brains. (B and C) Shown are the predicted effects that MG/MΦ exert on ECs (B) or on OL/OPCs (C) inferred by the CellChat R package. All probable ligand–receptor (L–R) pairs and their categories are listed. The sizes of the dots represent the probability of the L–R pairs. The L–R pairs specific to the young and aged groups are colored in green and red, respectively.