Skip to main content
. Author manuscript; available in PMC: 2023 Jun 23.
Published in final edited form as: ACS Chem Neurosci. 2020 Oct 7;11(20):3245–3258. doi: 10.1021/acschemneuro.0c00372

Figure 10.

Figure 10.

Detailed interaction of NAPQI in TrxR1 for hepatotoxicity. NAPQI has three possible binding poses with TrxR1 because of the (1) steric interaction with Cys59 (4.3 Å), (2) hydrogen bonding with Cys497 (2.9 Å), and (3) hydrogen bonding with Cys498 (3.1 Å). PDB ID 2ZZ0.