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. Author manuscript; available in PMC: 2023 Jun 23.
Published in final edited form as: ACS Chem Neurosci. 2020 Oct 7;11(20):3245–3258. doi: 10.1021/acschemneuro.0c00372

Figure 8.

Figure 8.

Observed and simulated concentration–time profiles of (a) acetaminophen 1000 mg iv bolus and (b) fentanyl 7 mg iv bolus. The simulated results were generated using 10 trials of 10 virtual healthy volunteers. Observed data are highlighted in red dots, while the simulated results, mean value, and 95th/5th percentile of the simulation are shown by corresponding lines.