Table 5. . Cardiac or renal involvement and most frequent diagnosis (admitting and primary), stratified by discharge status.
| Discharge status | Adult AL amyloidosis patients n (%) = 1341 (100%) |
p-value | ||
|---|---|---|---|---|
| In-hospital death n (%) = 107 (8.0%) |
Discharged alive n (%) = 1234 (92.0%) |
|||
| Cardiac or renal involvement, n (Col%) (Row%) | <0.001 | |||
| Cardiac and renal | 85 (79.4) [11.6] | 649 (52.6) [88.4] | 734 (54.7) [100.0] | |
| Cardiac only | 7 (6.5) [4.0] | 169 (13.7) [96.0] | 176 (13.1) [100.0] | |
| Renal only | 13 (12.1) [4.2] | 296 (24.0) [95.8] | 309 (23.0) [100.0] | |
| No cardiac or renal involvement | 2 (1.9) [1.6] | 120 (9.7) [98.4] | 122 (9.1) [100.0] | |
| Most frequent admitting diagnosis, by cohort, n (%) | ||||
| Unknown | 8 (7.5) | 125 (10.1) | – | – |
| Shortness of breath | 10 (9.4) | 98 (7.9) | – | – |
| Sepsis, unspecified organisms | 9 (8.4) | – | – | – |
| Light chain (AL) amyloidosis | – | 72 (5.8) | – | – |
| Acute kidney failure, unspecified | – | 65 (5.3) | – | – |
| Most frequent primary diagnosis, by cohort, n (%) | – | |||
| Light chain (AL) amyloidosis | 18 (16.8) | 222 (18.0) | – | – |
| Sepsis, unspecified organisms | 12 (11.2) | – | – | – |
| Hypertensive heart and CKD w/HF and stage 1–4 CKD or unspecified CKD | 11 (10.3) | 73 (5.9) | – | – |
| Acute kidney failure, unspecified | 6 (5.6) | 70 (5.7) | – | – |
| Organ-limited amyloidosis | 6 (5.6) | – | – | – |
| MM not having achieved remission | – | 67 (5.4) | – | – |
AL: Systemic amyloid light chain; CKD: Chronic kidney disease; HF: Heart failure; MM: Multiple myeloma; SD: Standard deviation.