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. Author manuscript; available in PMC: 2023 Jun 23.
Published in final edited form as: J Pediatr. 2022 Jan 12;244:64–71.e2. doi: 10.1016/j.jpeds.2021.12.070

Table II.

NEC outcomes

Outcomes All VLBWs ELBWs (<1000 g)
No EVC001 (N = 301) EVC001 (N = 182) P value No EVC001 (N = 125) EVC001 (N = 75) P value
NEC, % 11.0 2.7 <.01* 19.2 5.3 <.01*
RR (95% CI) 0.27 (0.09–0.61) <.01 0.28 (0.09–0.70) .02
NNT (95% CI) 13 (10.0–23.5) 8 (5.7–17.3)
NEC-related mortality, % 2.7 0 .03* 5.6 0 <.05*
NEC onset, day of life, mean 23.5 16.8 .30 24.0 19.3 .65
Medical NEC (Bell stage II), % 7.0 1.1 <.01* 12.0 2.7 .03*
Surgical NEC (Bell stage III), % 4.0 1.6 .18* 7.2 2.7 .21*
*

By the Fisher exact test.

By log binomial regression adjusted for sex, birth weight, gestational age at birth, and mode of delivery.

By the Wilcoxon rank-sum test.