Table II.
Outcomes | All VLBWs | ELBWs (<1000 g) | ||||
---|---|---|---|---|---|---|
No EVC001 (N = 301) | EVC001 (N = 182) | P value | No EVC001 (N = 125) | EVC001 (N = 75) | P value | |
NEC, % | 11.0 | 2.7 | <.01* | 19.2 | 5.3 | <.01* |
RR (95% CI) | 0.27 (0.09–0.61) | <.01† | 0.28 (0.09–0.70) | .02† | ||
NNT (95% CI) | 13 (10.0–23.5) | 8 (5.7–17.3) | ||||
NEC-related mortality, % | 2.7 | 0 | .03* | 5.6 | 0 | <.05* |
NEC onset, day of life, mean | 23.5 | 16.8 | .30‡ | 24.0 | 19.3 | .65‡ |
Medical NEC (Bell stage II), % | 7.0 | 1.1 | <.01* | 12.0 | 2.7 | .03* |
Surgical NEC (Bell stage III), % | 4.0 | 1.6 | .18* | 7.2 | 2.7 | .21* |
By the Fisher exact test.
By log binomial regression adjusted for sex, birth weight, gestational age at birth, and mode of delivery.
By the Wilcoxon rank-sum test.