Figure 2. Alcohol versus placebo intake experimental manipulation:
(A) In the pre-scan ATT, groups did not differ in alcohol/placebo intake amounts (F(1,100)=0.03, p=0.87), nor within groups across sessions, (BD: t(52)=0.15, p=0.88; SD: t(50)=0.29, p=0.77), indicating no differences between groups in initial alcohol self-motivation. (B) Significantly higher breath alcohol levels were observed in the alcohol vs placebo Session (F(1,536)=121.5, p<0.0001) across both groups, with no group differences at any point during the experiment (Peak BrAC mean: BD - 0.026 +/− 0.005; SD - 0.017 +/− 0.003). (C) Heart rate assessed during initial 30 minutes after Pre-Scan ATT increased in both groups in the alcohol compared to placebo Session (F(1,100)=8.1, p=0.005). (D) Sustained alcohol self motivation assessed as change in the post-pre scan ATT for alcohol relative to the placebo session indicated BD consumed significantly more amounts than SD (t(50)=2.55, p=0.01, and with no differences between groups in the post- pre amount for the placebo session (t(50)=08, p=0.43).