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. 2023 Jul;75(4):789–814. doi: 10.1124/pharmrev.122.000810

Fig. 4.

Fig. 4

Use of biomarkers in personalized medicine. Panels include phenotypic and genomic markers. Note that germline mutations can be detected at any time, whereas other markers, including somatic mutations, vary with disease state, age, drug treatment, and other factors.