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. 2023 Jun 23;18(6):e0278441. doi: 10.1371/journal.pone.0278441

Table 4. Average levels of renal markers among seropositive RA subjects and seronegative controls.

Renal Markers (Unit) Female Male
Seropositive RA Control p value Seropositive RA Control p value
Mean ± SD Mean ± SD Mean ± SD Mean ± SD
eGFR 86.9±21 94.2±20.3 <0.000001 80.5±17.8 84.7±17.6 <0.000001
BUN/creatinine 20.3±6.5 19.5±6.1 <0.000001 17.5±5.9 17.3±5.2 0.163
BUN (mg/dL) 14.8±5.1 13.8±4.7 <0.000001 17.2±5.7 16.5±5.5 <0.00001
Creatinine (Mg/Dl) 0.8±0.6 0.7±0.2 <0.001 1.0±0.2 1.0±0.2 0.042
Cystatin C (mg/L) 0.9±0.3 0.9±0.2 <0.000001 1.0±0.3 0.9±0.2 <0.000001
Albumin (G/Dl) 4.5±0.3 4.6±0.3 <0.000001 4.6±0.3 4.7±0.3 <0.000001
Sodium (Mmol/L) 141.5±3 141.7±2.9 0.002 141.8±2.9 142.1±2.8 0.006
Potassium (Mmol/L) 4.4±0.4 4.4±0.4 0.461 4.5±0.4 4.5±0.4 0.053
Chloride (Mmol/L) 101.2±3 101.6±2.9 <0.000001 100.9±3.1 101.2±2.8 0.002
Total Bicarbonate (Mmol/L) 22.5±3 22.3±2.9 0.004 22.6±3.1 22.7±3.1 0.313
Calcium (Mg/Dl) 9.6±0.5 9.6±0.4 0.002 9.6±0.5 9.7±0.4 0.034
Phosphate (Mg/Dl) 3.7±0.5 3.7±0.5 0.002 3.4±0.6 3.5±0.6 <0.000001
Magnesium (Mg/Dl) 2.1±0.2 2.1±0.2 0.060 2.1±0.2 2.1±0.2 0.308