Fig 9. Voxel-wise classification of histological patterns.

Rat histological example data showing Regional damage of the left and right (experimental) nerves. The two optic nerves are shown in three different slices in rostro-caudal order. Photomicrographs of the same experimental nerve at approximately the same locations show clearly demarcated areas of Injured and Intact histological patterns, that correspond to the voxel-wise classification of the DW-MRI of the experimental nerve. The few voxels incorrectly classified as Injured in the left (control) nerve likely result from partial volume effects.