Fig 1. Calculation of time-to-reinfection based on infection episodes and on type-specific episodes.

Illustration using mock data of the calculation of time-to-reinfection for 3 participants with multiple episodes. Dots indicate beginning and end of episodes, which are joined by horizontal bars. Gray shaded area indicates the time period of continuous P. falciparum positivity. Labels between bars indicate either time-to-reinfection (in days) or censoring following the end of an episode. (A) Pf infection indicates episodes of infection with P. falciparum. (B) Epitope X indicate episodes of infection with specific epitope types of P. falciparum, which are classified on the basis of translated nucleotide sequences of csp and ama1. Colors indicate unique CSP or AMA-1 epitopes which comprise multi-clonal infections of P falciparum.