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. 2023 Jun 12;19(6):e1011442. doi: 10.1371/journal.ppat.1011442

Fig 4. Time to reinfection by homologous P. falciparum parasites stratified by symptomaticity of index infection.

Fig 4

A) Kaplan-Meier survival curves of time to reinfection by parasites with homologous CSP-Th2R, CSP-Th3R, and AMA-1 c1L type. Curves are probability stratified by index case as either asymptomatic (Asx, blue) or symptomatic (Sx, red). Crosses indicate index infections that were censored at the end of the study period. Vertical dotted line indicates the start of the defined time at risk of re-infection, shaded areas indicate the 95% confidence interval, and table shows the number of participants at risk stratified by symptomaticity of index infection at day 0, 100, 200, 300, and 400. B) Adjusted Hazard Ratios estimated by multivariate mixed effects Cox proportional hazards models for reinfection by parasites bearing homologous CSP-Th2R, CSP-Th3R, and AMA-1 c1L epitope types. See methods for variable definitions and reference cateogries. Diamonds indicate adjusted HRs, and bars show the 95% CIs. Adj. HR, Adjusted Hazard Ratio.