Table 1.
Demographic and clinical characteristics of the samples of the studies revised
| Authors | n | Operation details (RS, RF, TL-MRGFU)a | Settings (software, ablation equipment)a | Mean age symptoms initial occurrence (mean years, SD)a | Mean symptom/illness duration (mean years, SD)a | Mean age at surgery (mean years, SD)a | Follow-up (m)a | Mean Y-BOCS (Prea) | Mean Y-BOCS (Posta) |
|---|---|---|---|---|---|---|---|---|---|
| Capsulotomies | |||||||||
| Fodstad et al. (1982) | 2 | RF | Air Ventriculography | Not reported | 23 | 47 | Before discharge, 1w, 1, 3, 6, 12, ≥ 12 | Not reported | Not reported |
| Oliver et al. (2003) | 15 | RF – 75ºC | Brainlab, Radionics RF3 | 16.3 (9.6) | 18.1 (5.6) | 34.2 (8.2) | 1, 2, 3, 6, 9, 12 | 29.67 | 19.12 |
| Rück et al. (2008) | 23 |
RF – 60º (n = 12) RS – 160 to 200 Gy (n = 9) |
Gamma Knife (Elekta Instr.) | Not reported | 21 (8) | 41 (11) | 12, 129 | 34.0 (3.4) | 18.9 (12.0) |
| Csigó et al. (2010) | 5 | RF | Brainlab, Radionics | 9 (6.74) | Not reported | 32.2 (6.3) | 1, 6, 12, 24 | 38.2 (1.78) | 26.4 (5.12) |
| Jung et al. (2014) | 4 | TL-MRGFU – 51-56º | ExAblate 4000 | Not reported | 16.3 (5.7) | Not reported | 1w, 1, 3, 6, 9 | 35.3 (1.9) | 32 (3.3) |
| Zhan et al. (2014) | 53 | RF – 80º | Radionics RF3 | Not reported | 8.09 (2.99) | 28.89 (9.16) | 2w, 12, 36, 60 | 24.7 (4) | 6.1 (4.8) |
| Batistuzzo et al. (2015) | 17 | RS-GK – 180 Gy (max) | Gamma Knife Model B (Elekta Instr.) | 11.3 (5) | 22.4 (12.8) | 34.4 (10.6) | 12, 24 | 32.9 (2.6) | 21.4 (11.7) |
| Gong et al. (2018) | 14 | RF – 75º | SurgiPlan, Elekta neurostimulator | Not reported | 12.6 (10) | 31 (3.1) | 1, 3, 6, 12 | 29.2 (5.37) | 16.5 (4.78) |
| Kim et al. (2018) | 11 | TL-MRGFU – 51-56º | ExAblate 4000 | Not reported | Not reported | Not reported | 1w, 1, 3, 6, 12, 24 | 34.4 (2.3) | 30.3 (4.3) |
| Peker et al. (2020) | 21 | RS-GK – 140–150 Gy | Gamma Knife 4C and Perfexion unit | Not reported | 11.9 (5.23) | 32.8 (7.61) | 6, 12, 24, 36 | 35.7 (3.99) | 29.9 (6.09) |
| Krámska et al. (2021) | 12 | RF-78–85° | SurgiPlan, 16-G, Diros Technology | 18.17 (8.58) | 21.42 | 39.7 (8.44) | 6 | 31.67 (6.73) | 16.58 (7.44) |
| Kassel et al. (2022) | 9 | RS-GK – 180 Gy (max) | Leksell Gamma Knife model U and C | Not reported | Not reported | Not reported | 6, 12, 24, 60 | 33.6 (3.93) | 22.68 (7.87) |
| Cingulotomies | |||||||||
| Fodstad et al. (1982) | 2 | RF | Air Ventriculography | Not reported | 23 | 47 | Before discharge, 1w, 1, 3, 6, 12, ≥ 12 | Not reported | Not reported |
| Jung et al. (2006) | 17 | RF – 85º | Radionics RFG-3, Radionics | 24.6 (9.8) | 10.9 (5.2) | 36.1 (9.4) | 12, 24 | 35 (3.86) | 22.4 (6.49) |
RS, radiosurgery; RF, radiofrequency; TL-MRGFU, thermal lesioning by magnetic resonance-guided focused ultrasound; SD, standard deviation; Y-BOCS, yale-brown obsessive–compulsive scale; NR, not reported; Gy, grays; w, week; RS-GK, radiosurgery
aData obtained from the full sample