Table 1.
Demographics and baseline characteristics
| Characteristic |
Normal Hepatic Function (n=9) |
Mild (Child-Pugh A) Hepatic Impairment (n=6) |
Moderate (Child-Pugh B) Hepatic Impairment (n=6) |
Severe (Child-Pugh C) Hepatic Impairment (n=6) |
|---|---|---|---|---|
| Age, median (range), years | 57.0 (44–65) | 54.5 (49–60) | 58.0 (48–62) | 59.0 (53–65) |
| Male, n (%) | 7 (77.8) | 5 (83.3) | 6 (100) | 3 (50.0) |
| Race, n (%) | ||||
| White | 8 (88.9) | 5 (83.3) | 6 (100) | 6 (100) |
| Black or African American | 1 (11.1) | 0 | 0 | 0 |
| Asian | 0 | 1 (16.7) | 0 | 0 |
| Ethnicity, n (%) | ||||
| Hispanic or Latino | 5 (55.6) | 3 (50.0) | 2 (33.3) | 1 (16.7) |
| Not Hispanic or Latino | 4 (44.4) | 3 (50.0) | 4 (66.7) | 5 (83.3) |
| BMI, mean (SD), kg/m2 | 28.7 (3.68) | 29.0 (3.02) | 30.7 (4.56) | 30.3 (2.74) |
| Smoking history, n (%) | ||||
| Never smoked | 4 (44.4) | 0 | 3 (50.0) | 2 (33.3) |
| Currently smoking | 4 (44.4) | 4 (66.7) | 3 (50.0) | 2 (33.3) |
| Formerly smoked | 1 (11.1) | 2 (33.3) | 0 | 2 (33.3) |
BMI body mass index, SD standard deviation