Table 1.
Characteristics of the included studies
| First author | Year | Surgery type | Sample size (A/B) | Mean age (A/B) | Sex (M/F) | Intervention (A/B) | Outcome indicators | Jada scores |
|---|---|---|---|---|---|---|---|---|
| Bian [13] | 2018 | AKR | 98 (46/42) | 66.64 ± 7.27/66.12 ± 8.34 | 24/64 |
A: 40 mg of parecoxib sodium was injected intravenously 30 min before surgery and 12 h after surgery B: Inject the same dose of normal saline at the same time |
①②③ | 4 |
| Han [14] | 2014 | AKR | 40 (20/20) | – | 18/22 |
A: Parecoxib sodium 40 mg was given intravenously 30 min before surgery and every 12 h within 2 days after surgery B: Inject the same dose of normal saline at the same time |
① | 1 |
| Huang [15] | 2012 | AKR | 30 (15/15) | – | – |
A: Parecoxib sodium 40 mg was given intravenously 15 min before and 12 h after surgery B: Inject the same dose of normal saline at the same time |
① | 2 |
| Martinez [16] | 2007 | AHR | 43 (22/21) | 65 ± 9/63 ± 11 | 24/19 |
A: Parecoxib 40 mg was injected intravenously at the time of anesthesia induction and 12 h after surgery B: Inject the same dose of normal saline at the same time |
①②③ | 5 |
| Peng [17] | 2018 | AHR | 94 (48/46) | 57.22 ± 12.51/55.19 ± 10.97 | 38/56 |
A: Parecoxib sodium 20 mg intravenously is given 30 min before surgery and every 12 h for 2 days after surgery B: Inject the same dose of normal saline at the same time |
①③ | 4 |
| Xiao [18] | 2019 | AHR | 141 (69/72) | 53.79 ± 12.46/54.35 ± 11.93 | – |
A: Parecoxib sodium 40 mg intravenously every 12 h 30 min before and 2 days after surgery B: Inject the same dose of normal saline at the same time |
①②③ | 5 |
| Xiao [19] | 2014 | AHR | 29 (15/14) | 52 ± 12/55 ± 14 | 17/12 |
A: Parecoxib sodium 40 mg was injected intravenously 30 min before excision, 9 p.m. after surgery, and every 12 h for 2 days after surgery B: Inject the same dose of normal saline at the same time |
①②③ | 6 |
| Xiao [19] | 2014 | AKR | 38 (19/19) | 67 ± 8/66 ± 8 | 13/25 |
A: Parecoxib sodium 40 mg was injected intravenously 30 min before excision, 9 p.m. after surgery, and every 12 h for 2 days after surgery B: Inject the same dose of normal saline at the same time |
①②③ | 6 |
| Zhao [20] | 2010 |
AHR AKR |
42 (20/22) | 71.1 ± 4.4/70.5 ± 4.9 | 19/23 |
A: Parecoxib 40 mg was given intravenously 15 min before anesthesia induction and 12 h postoperatively B: Inject the same dose of normal saline at the same time |
① | 1 |
| Zhu [21] | 2016 | AKR | 122 (60/62) | 75.1 ± 8.2/74.3 ± 7.6 | – |
A: Intravenous parecoxib sodium 40 mg was given intravenously before and 12 h after surgery B: Inject the same dose of normal saline at the same time |
① | 4 |
A parecoxib group, B placebo group, M male, F female, ① VAS scores, ② Cumulative opioids consumption, ③ Incidence of adverse reactions; Jadad scores were based on an improved Jadad Scale (a score of 1–3 is considered a low-quality study, and a score of 4–7 is considered a high-quality study)