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. 2023 Jun 23;14:107. doi: 10.1007/s12672-023-00715-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Proteomic analysis of high-risk prostate cancer. A, B Volcano map and heat map of differentially expressed protein. C, D Enrichment analysis of up-regulated and down-regulated protein WIKI pathways. E The heatmaps depicting the differential expression of Heat Shock Proteins (HSPs) at the mRNA level were obtained from the TCGA-PRAD database. F The heatmaps depicting the differential expression of Heat Shock Proteins (HSPs) at the protein level were obtained from our proteomic data. G The Venn graph shows intersection of differentially expressed HSPs in mRNA level and protein level. H Distribution of differentially expressed HSPs (According to molecular mass)